| 1 |
First clinical study of a pegylated diabody 124 I-labeled PEG-AVP0458 in patients with tumor-associated glycoprotein 72 positive cancers. Theranostics. 2020 Sep 15;10(25):11404-11415.
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| 2 |
Development of bispecific anti-c-Met/PD-1 diabodies for the treatment of solid tumors and the effect of c-Met binding affinity on efficacy. Oncoimmunology. 2021 Jul 21;10(1):1914954.
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| 3 |
"Diabodies": small bivalent and bispecific antibody fragments. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6444-8.
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| 4 |
Harnessing the hERG1/1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers. Mol Cancer Ther. 2021 Aug;20(8):1338-1349.
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| 5 |
Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications. J Immunol Methods. 2001 Jul 1;253(1-2):195-208.
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| 6 |
The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility. J Mol Biol. 2003 Feb 14;326(2):341-51.
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| 7 |
Generation of high-affinity, internalizing anti-FGFR2 single-chain variable antibody fragment fused with Fc for targeting gastrointestinal cancers. PLoS One. 2018 Feb 8;13(2):e0192194.
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| 8 |
Crystal structures of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep. 2016 Sep 29;6:34515.
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| 9 |
Synthesis, Positron Emission Tomography Imaging, and Therapy of Diabody Targeted Drug Lipid Nanoparticles in a Prostate Cancer Murine Model. Cancer Biother Radiopharm. 2017 Sep;32(7):247-257.
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| 10 |
Monodispersed DOTA-PEG-conjugated anti-TAG-72 diabody has low kidney uptake and high tumor-to-blood ratios resulting in improved 64Cu PET. J Nucl Med. 2010 Jul;51(7):1139-46.
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| 11 |
Optimized Expression and Characterization of a Novel Fully Human Bispecific Single-Chain Diabody Targeting Vascular Endothelial Growth Factor165 and Programmed Death-1 in Pichia pastoris and Evaluation of Antitumor Activity In Vivo. Int J Mol Sci. 2018 Sep 25;19(10):2900.
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| 12 |
Isolation and characterization of human anti-VEGF165 monoclonal antibody with anti-tumor efficacy from transgenic mice expressing human immunoglobulin loci. Cancer Lett. 2009 Jan 8;273(1):28-34.
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| 13 |
18 F-labeled anti-human CD20 cys-diabody for same-day immunoPET in a model of aggressive B cell lymphoma in human CD20 transgenic mice. Eur J Nucl Med Mol Imaging. 2019 Feb;46(2):489-500.
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| 14 |
ImmunoPET of Malignant and Normal B Cells with 89 Zr- and 124 I-Labeled Obinutuzumab Antibody Fragments Reveals Differential CD20 Internalization In Vivo. Clin Cancer Res. 2017 Dec 1;23(23):7242-7252.
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| 15 |
A tetravalent single chain diabody (CD40/HER2) efficiently inhibits tumor proliferation through recruitment of T cells and anti-HER2 functions. Mol Immunol. 2019 May;109:149-156.
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| 16 |
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. J Clin Invest. 2016 Jul 1;126(7):2610-20.
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| 17 |
Process development of a human recombinant diabody expressed in E. coli: engagement of CD99-induced apoptosis for target therapy in Ewing's sarcoma. Appl Microbiol Biotechnol. 2016 May;100(9):3949-63.
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| 18 |
Functional Domain Order of an Anti-EGFR G Anti-CD16 Bispecific Diabody Involving NK Cell Activation. Int J Mol Sci. 2020 Nov 24;21(23):8914.
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| 19 |
Humanization of the bispecific epidermal growth factor receptor x CD3 diabody and its efficacy as a potential clinical reagent. Clin Cancer Res. 2006 Jul 1;12(13):4036-42.
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| 20 |
Domain order of a bispecific diabody dramatically enhances its antitumor activity beyond structural format conversion: the case of the hEx3 diabody. Protein Eng Des Sel. 2013 May;26(5):359-67.
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| 21 |
Fine epitope mapping of a human disulphide-stabilized diabody against fibroblast growth factor-2. J Biochem. 2019 Jun 1;165(6):487-495.
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| 22 |
Inhibition activity of a disulfide-stabilized diabody against basic fibroblast growth factor in lung cancer. Oncotarget. 2017 Mar 21;8(12):20187-20197.
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| 23 |
Construction of a disulfide-stabilized diabody against fibroblast growth factor-2 and the inhibition activity in targeting breast cancer. Cancer Sci. 2016 Aug;107(8):1141-50.
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| 24 |
ImmunoPET Imaging of Murine CD4 + T Cells Using Anti-CD4 Cys-Diabody: Effects of Protein Dose on T Cell Function and Imaging. Mol Imaging Biol. 2017 Aug;19(4):599-609.
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| 25 |
Balanced secretion of anti-CEA G anti-CD3 diabody chains using the 2A self-cleaving peptide maximizes diabody assembly and tumor-specific cytotoxicity. Gene Ther. 2017 Apr;24(4):208-214.
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| 26 |
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands. Cell. 2015 Mar 12;160(6):1196-208.
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Crystal structure of a diabody, a bivalent antibody fragment. Structure. 1994 Dec 15;2(12):1217-26.
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Fluorescent Image-Guided Surgery with an Anti-Prostate Stem Cell Antigen (PSCA) Diabody Enables Targeted Resection of Mouse Prostate Cancer Xenografts in Real Time. Clin Cancer Res. 2016 Mar 15;22(6):1403-12.
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| 29 |
A Dual-Modality Linker Enables Site-Specific Conjugation of Antibody Fragments for 18 F-Immuno-PET and Fluorescence Imaging. J Nucl Med. 2019 Oct;60(10):1467-1473.
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| 30 |
A novel in vitro ELISA for estimation of glycoprotein content in human rabies vaccines. J Immunoassay Immunochem. 2017;38(4):400-410.
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