Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003583) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Diabody anti-c-Met/PD-1 Diabody-mp
|
|||||
| Synonyms |
Diabody-mp
|
|||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | HEK293E cells | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS031 | [1] | ||||
| Scaffold Name | Diabody | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Programmed cell death protein 1 | inhibitor | Tumors [ICD-11: XH1N44] | Kd: 0.63 nM | Fudan University | [1] | |
| Hepatocyte growth factor receptor | inhibitor | Tumors [ICD-11: XH1N44] | Kd: 0.63 nM | Fudan University | [1] | |