General Information of Synthetic Binding Protein (SBP) (ID: SBP001000)
SBP Name
Diabody anti-Phenyloxazolone (VHNQ11-VLNQ11)2
Synonyms
Diabody (VHNQ11-VLNQ11)2
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
Template Name Monoclonal antibody NQ11.7.22 (NQ11)
Protein Scaffold Information of This SBP
Scaffold ID PS031
Scaffold Info
[1]
Scaffold Name Diabody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Phenyloxazolone
BTS Info
Binder Tools for constructing small bivalent and bispecific antibody fragments in bacteria N.A. Medical Research Council Centre for Protein Engineering [1]
References
1 "Diabodies": small bivalent and bispecific antibody fragments. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6444-8.