General Information of Synthetic Binding Protein (SBP) (ID: SBP001015)
SBP Name
Diabody anti-PSMA cys-clone
Synonyms
Anti-PSMA cDb
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Expi293F?human cells
Highest Status Research
Template Name Monoclonal antibody J591
Protein Scaffold Information of This SBP
Scaffold ID PS031
Scaffold Info
[1]
Scaffold Name Diabody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Glutamate carboxypeptidase 2
BTS Info
Binder Prostate Cancer [ICD-11: 2C82.Z] N.A. City of Hope National Medical Center [1]
References
1 Synthesis, Positron Emission Tomography Imaging, and Therapy of Diabody Targeted Drug Lipid Nanoparticles in a Prostate Cancer Murine Model. Cancer Biother Radiopharm. 2017 Sep;32(7):247-257.