General Information of Synthetic Binding Protein (SBP) (ID: SBP001012)
SBP Name
Diabody anti-CD99 C7
Synonyms
Diabody C7
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS031
Scaffold Info
[1]
Scaffold Name Diabody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
CD99 antigen
BTS Info
Binder Ewing sarcoma [ICD-11: XH8KJ8] N.A. Diatheva S.R.L [1]
References
1 Process development of a human recombinant diabody expressed in E. coli: engagement of CD99-induced apoptosis for target therapy in Ewing's sarcoma. Appl Microbiol Biotechnol. 2016 May;100(9):3949-63.