Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001005) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Diabody anti-ERBB1/CD16 hEx16-HL
|
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| Synonyms |
Diabody hEx16-HL
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli; Brevibacillus choshinensis | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS031 | [1] | ||||
| Scaffold Name | Diabody | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Fc-gamma receptor IIIb | Activator | Research tool | Kd: 591 nM | Tokyo University of Agriculture and Technology | [1] | |
| Epidermal growth factor receptor | Activator | Research tool | Kd: 85.7 nM | Tokyo University of Agriculture and Technology | [1] | |