Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001001) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Diabody anti-HEWL (VHD1.3-VLD1.3)2
|
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| Synonyms |
Diabody (VHD1.3-VLD1.3)2
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli TG1 | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Template Name | Monoclonal antibody D1.3 | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS031 | [1] | ||||
| Scaffold Name | Diabody | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Hen egg-white lysozyme | Binder | Tools for constructing small bivalent and bispecific antibody fragments in bacteria | N.A. | Medical Research Council Centre for Protein Engineering | [1] | |