Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001026) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Diabody anti-PLC-delta-1 L5MK16
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| Synonyms |
Diabody L5MK16
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| Molecular Weight | 28.0 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| PDB ID | 1LMK | |||||
| Sequence Length | 263 | |||||
| SBP Sequence |
>Diabody anti-PLC-delta-1 L5MK16
QVQLQQSGTELMKPGRSLKISCKTTGYIFSNYWIEWVKQRPGHGLEWIGKILPGGGSNTY NDKFKGKATFTADTSSNIAYMQLSSLTSEDSAVYYCARGEDYYAYWYVLDYWGQGTTVTV SSGGGGSDIELTQSPLSLPVSLGDQASISCRSSQSLVHSNGNTSLHWYLKKPGQSPKLLI YKVSTRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPFTFGSGTKLELKR AAAEQKLISEEDLNGAA |
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| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS031 | [1] | ||||
| Scaffold Name | Diabody | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | Binder | Cancers [ICD-11: 2D4Z] | N.A. | Centre for Protein Engineering | [1] | |