Details of the PSS
| General Information of Protein Scaffold of SBP (PSS) (ID: PS036) | ||||||
|---|---|---|---|---|---|---|
| PSS Name |
GCN4-based binder
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| Synonyms |
Designed GCN4
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| Diagrammatic Sketch |
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| Highest Status | Research | |||||
| Class | Non-Antibody | |||||
| Fold Type | Two Alpha-Helices | |||||
| Thermal Denaturation TEMP | 68-84℃ | |||||
| Sequence Length | 31-37 | |||||
| Molecular Weight | 3-5 kDa | |||||
| Parental Protein of This PSS |
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| Parental Protein Name | Synonym | PDB ID | UniProt ID | Origin | ||
|---|---|---|---|---|---|---|
| GCN4 leucine zipper | leucine-zipper domain of the yeast transcription factor GCN4 | Saccharomyces cerevisiae; Synthetic construct | ||||
| Synthetic Binding Protein (SBP) Featuring this PSS |
|---|
| SBP Name | Highest Status | Template | Expression System | Selection Method | Details | Ref |
|---|---|---|---|---|---|---|
| GCN4-based binder anti-HIV-1 C34-GCN4 | Research | GCN4 | N.A. | Phage display | [1] | |
| GCN4-based binder anti-IL-4R-alpha 12CMAR-IL4 | Research | GCN4 | N.A. | N.A. | [2] | |
| GCN4-based binder anti-IL-4R-alpha 26CMAR-IL4 | Research | GCN4 | N.A. | N.A. | [2] | |
| GCN4-based binder anti-IL-4R-alpha MAR-IL4 | Research | GCN4 | N.A. | N.A. | [2] | |