Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003519) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Knottin MCoLib
|
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| Synonyms |
Knottin MCoLib
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS042 | [1] | ||||
| Scaffold Name | Knottin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Kallikrein-4 | Activator | Tools for regulating activity research | Kd: 0.07 nM | University of Queensland | [1] | |
| Coagulation factor XII | Activator | Tools for regulating activity research | Kd: 3.3 nM | University of Queensland | [1] | |
| Suppressor of tumorigenicity 14 protein | Activator | Tools for regulating activity research | Kd: 0.4 nM | University of Queensland | [1] | |