Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00578) | ||||||
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| BTS Name |
Kallikrein-4
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| Synonyms |
EC:3.4.21.; Enamel matrix serine proteinase 1; Kallikrein-like protein 1; KLK-L1; Prostase; Serine protease 17
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| BTS Type |
Protein
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| Family |
peptidase S1 family. Kallikrein subfamily
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| Gene Name |
KLK4
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| Organism |
Homo sapiens (Human)
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| Function |
Has a major role in enamel formation.; Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity).
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MATAGNPWGWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVL
VHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLI KLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK LYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNL CKFTEWIEKTVQAS |
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| Sequence Length |
254
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Knottin MCoLib | Research | Activator | Kd: 0.07 nM | Tools for regulating activity research | [1] | |