Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003222) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Bicyclic peptide anti-EphA2/CD137 BT7455
|
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| Synonyms |
Bicyclic peptide BT7455
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS017 | [1] | ||||
| Scaffold Name | Bicyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Tumor necrosis factor receptor superfamily member 9 | Agonist | Cancers [ICD-11: 2D4Z] | N.A. | Bicycle Therapeutics | [1] | |
| Ephrin type-A receptor 2 | Binder | Cancers [ICD-11: 2D4Z] | N.A. | Bicycle Therapeutics | [1] | |