General Information of Synthetic Binding Protein (SBP) (ID: SBP003221)
SBP Name
Bicyclic peptide anti-Nectin-4/CD137 BT7480
Synonyms
Bicyclic peptide BT7480
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS017
Scaffold Info
[1]
Scaffold Name Bicyclic peptide
Scaffold Class Non-Antibody
Fold Type Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Tumor necrosis factor receptor superfamily member 9
BTS Info
Agonist Cancers [ICD-11: 2D4Z] N.A. Bicycle Therapeutics [1]
Nectin-4
BTS Info
Binder Cancers [ICD-11: 2D4Z] N.A. Bicycle Therapeutics [1]
References
1 Bicycle therapeutics. Product Development Pipeline. 2021.