General Information of Synthetic Binding Protein (SBP) (ID: SBP000739)
SBP Name
Tendamistat-based binder anti-Integrin variants
Synonyms
Tendamistat-based binder variants
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS062
Scaffold Info
[1]
Scaffold Name Tendamistat-based binder
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Integrin alpha-v-beta-5
BTS Info
Binder Research tool N.A. University of Pennsylvania School of Medicine [1]
Integrin alpha-v-beta-3
BTS Info
Binder Research tool N.A. University of Pennsylvania School of Medicine [1]
Integrin alpha-IIb-beta-3
BTS Info
Binder Research tool N.A. University of Pennsylvania School of Medicine [1]
References
1 Use of phage display to probe the evolution of binding specificity and affinity in integrins. Protein Eng. 2003 Jan;16(1):65-72.