General Information of Protein Scaffold of SBP (PSS) (ID: PS062)
PSS Name
Tendamistat-based binder
Diagrammatic Sketch
Highest Status Research
Class Non-Antibody
Fold Type Beta-Sheets + Loops
Thermal Denaturation TEMP 46-87℃
Sequence Length 74-77
Molecular Weight 8-9 kDa
Parental Protein of This PSS
Parental Protein Name Synonym PDB ID UniProt ID Origin
Tendamistat Alpha-amylase inhibitor HOE-467A
1HOE
P01092
Streptomyces tendae; Synthetic construct
Synthetic Binding Protein (SBP) Featuring this PSS
SBP Name Highest Status Template Expression System Selection Method Details Ref
Tendamistat-based binder anti-mAbA8/Alpha-amylase A8-7 Research Tendamistat Escherichia coli Phage display
SBP Info
[1]
Tendamistat-based binder anti-Integrin variants Research N.A. N.A. Phage display
SBP Info
[2]
References
1 Tendamistat as a scaffold for conformationally constrained phage peptide libraries. J Mol Biol. 1995 Jul 21;250(4):460-70.
2 Use of phage display to probe the evolution of binding specificity and affinity in integrins. Protein Eng. 2003 Jan;16(1):65-72.