Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000588) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Alphabody anti-TNF-alpha/IL-23 CMX-02
|
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| Synonyms |
Alphabody IL-23 CMX-02
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS008 | [1] | ||||
| Scaffold Name | Alphabody | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Tumor necrosis factor | Binder | Psoriatic arthritis [ICD-11: FA21.Z]; Crohn disease [ICD-11: DD70.Z] | N.A. | Complix | [1] | |
| Interleukin-23 subunit alpha | Binder | Psoriatic arthritis [ICD-11: FA21.Z]; Crohn disease [ICD-11: DD70.Z] | N.A. | Complix | [1] | |