Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000372) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Affimer anti-PD-L1/LAG-3 AVA-021
|
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| Synonyms |
Affimer AVA-021
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS006 | [1] | ||||
| Scaffold Name | Affimer | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | One Alpha-Helix + Beta-Sheets+ Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Programmed cell death 1 ligand 1 | Inhibitor | Tumors [ICD-11: XH1N44] | N.A. | Avacta Group plc; Leeds Teaching Hospitals | [1] | |
| Lymphocyte activation gene 3 protein | Inhibitor | Tumors [ICD-11: XH1N44] | N.A. | Avacta Group plc; Leeds Teaching Hospitals | [1] | |