Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00580) | ||||||
|---|---|---|---|---|---|---|
| BTS Name |
Serine protease 1
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| Synonyms |
EC:3.4.21.4; Anionic trypsin I; Anionic trypsin-I; Beta-trypsin; Cationic trypsin; Pretrypsinogen I; Trypsin I; Trypsin-I
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| BTS Type |
Protein
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| Family |
peptidase S1 family
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| Gene Name |
PRSS1
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| Organism |
Bos taurus (Bovine)
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK QTIASN |
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| Sequence Length |
246
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Knottin anti-FXIIa cMCoFx1 | Research | Inhibitor | Ki: 1110 nM | Tools for inhibiting Human beta-Factor XIIa | [1] | |
| Knottin anti-FXIIa cMCoTI-fxL1 | Research | Inhibitor | Ki: 996 nM | Tools for inhibiting Human beta-Factor XIIa | [1] | |
| Knottin anti-FXIIa cMCoTI-fxL5 | Research | Inhibitor | Ki: 0.08 nM | Tools for inhibiting Human beta-Factor XIIa | [1] | |