General Information of Binding Target of SBP (BTS) (ID: ST00196)
BTS Name
Centriole protein
BTS Type
Protein
Gene Name
CrSAS-6
Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
UniProt ID
A9CQL4
UniProt Entry
A9CQL4_CHLRE
PFam
PF16531
Sequence
MPLLLDDGDPKAQTGFDLSTATTLFWRPVPVHVKQQDREDVLEELTFRILTGVAKQNHNL
RILRIHISSDSDLFFLHTLEVSEEDFQSLKNDQGILVDFASFPGKIISLLEKCILAQPGD
SPRFQAVLTIRGGESVFKIVEINDFKQLPHITLAFRPGNDSVVKQFLAFRLSEVKGTCHD
LSDDLSRTRDDRDSMVAQLAQCRQQLAQLREQYDKHLLEVQAQAKTQQASAHEERIREKS
QLKDQFEKERGEMEGRYRDQIAALNTRLGELDTENRKLREVKYELDTKVSELSHKLGSSE
GSNRSLEEETARLRSLNQQLSSSKHELEIQLNEAKAKVLALDEKAQSQGDVIEQQRGRLR
DMEAALRQTEQRCADLRDTLASAEGRAKEAQAEVLKGNQAIEKLTNDLRLAKEKTKRKAA
IILRQEEELQEREQSLANATRDVGVLGQQAESLRKDVASLHSENDSLRSKLEDSKQQLQS
NEQMIRWLNQQVTEAQLHASGATVAGSRYAFRPSAALPGSMPPPSVAATPAVGLLAAPGP
STAYKPGGTTSRYASTLGVTGLSSGLSGAGATSVGAAVAGGSYGAGGDSSYRPGVGGAYA
SSGGAGGFGGSVGGGGQVGGSGSAIGAATGAGSALGTYRSSYAASTHPSPGGVTAGMGST
LTTPAVNRYAAGSYSSVSSSLSFGGGLGAARAVDATPAASKYGVGFSNAAMGVVGTVGGA
GGTDAQRA
Sequence Length
728
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Monobody anti-CrSAS-6 clone 1 Research Binder Kd: 566 nM Tools for tuning SAS-6 architecture
SBP Info
[1]
Monobody anti-CrSAS-6 clone 13 Research Binder Kd: 134 nM Tools for tuning SAS-6 architecture
SBP Info
[1]
Monobody anti-CrSAS-6 clone 15 Research Binder Kd: 137 nM Tools for tuning SAS-6 architecture
SBP Info
[1]
References
1 Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun. 2021 Jun 21;12(1):3805.