General Information of Synthetic Binding Protein (SBP) (ID: SBP003135)
SBP Name
Monobody anti-CrSAS-6 clone 1
Synonyms
MB-CRS6-1
Molecular Weight 10 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21 (DE3)
Selection Method Phage display and yeast display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS047
Scaffold Info
[1]
Scaffold Name Monobody
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Centriole protein
BTS Info
Binder Tools for tuning SAS-6 architecture Kd: 566 nM Swiss Federal Institute of Technology Lausanne (EPFL) [1]
References
1 Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun. 2021 Jun 21;12(1):3805.