Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00104) | ||||||
|---|---|---|---|---|---|---|
| BTS Name |
Mast cell tryptase beta III
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| BTS Type |
Protein
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| Gene Name |
tryptaseB
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| Organism |
Homo sapiens (Human)
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Sequence |
MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCG
GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQVATAPHTFPAPS |
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| Sequence Length |
233
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Cyclotide anti-Mast cell tryptase beta MCoEETI(KKV) | Research | Inhibitor | Kd: 1 nM | Allergic asthma [ICD-11: CA23.02]; Inflammatory disorders [ICD-11: 4A6Z] | [1] | |
| Cyclotide anti-Mast cell tryptase beta MCoEETI(SDG) | Research | Inhibitor | N.A. | Allergic asthma [ICD-11: CA23.02]; Inflammatory disorders [ICD-11: 4A6Z] | [1] | |
| Knottin anti-Mast cell tryptase beta oMCoEETI(KKV) | Research | Inhibitor | N.A. | Allergic asthma [ICD-11: CA23.02]; Inflammatory disorders [ICD-11: 4A6Z] | [1] | |