Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003620) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
DARPin anti-IgE E07
|
|||||
| Synonyms |
DARPin E07
|
|||||
| Thermal Denaturation TEMP | 72.1 ℃ | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | yeast display | |||||
| Highest Status | Research | |||||
| Template Name | E3_53 T48N | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS027 | [1] | ||||
| Scaffold Name | DARPin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Immunoglobulin E | Inhibitor | Allergies [ICD-11: 4A84.Z] | Kd: 3.4 nM | Stanford University | [1] | |