Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003595) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-NTS2 CR-01-64
|
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| Synonyms |
Macrocyclic peptide CR-01-64
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Template Name | Neurotensin (8-13) | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Neurotensin receptor type 2 | Inhibitor | Tools for analgesic effect | Ki: 7.0 nM | Universit de Sherbrooke | [1] | |
| Neurotensin receptor type 1 | Inhibitor | Tools for analgesic effect | Ki: 871 nM | Universit de Sherbrooke | [1] | |