Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00596) | ||||||
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| BTS Name |
Neurotensin receptor type 2
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| Synonyms |
NT-R-2; NTR2; Levocabastine-sensitive neurotensin receptor
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| BTS Type |
Protein
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| Family |
G-protein coupled receptor 1 family;
Neurotensin receptor subfamily; NTSR2 sub-subfamily |
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| Gene Name |
NTSR2
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| Organism |
Homo sapiens (Human)
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| Function |
Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKA
RAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAY ATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHEL ETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQV PSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLR AIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNA VSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT |
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| Sequence Length |
410
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Macrocyclic peptide anti-NTS2 CR-01-64 | Research | Inhibitor | Ki: 7.0 nM | Tools for analgesic effect | [1] | |