General Information of Synthetic Binding Protein (SBP) (ID: SBP003536)
SBP Name
vNAR anti-SARS-CoV-2 SP240
Synonyms
vNAR SP240
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21 (DE3)
Selection Method phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS065
Scaffold Info
[1]
Scaffold Name vNAR
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
Neutralizer SARS-CoV-2 [ICD-11: XN109] N.A. Centro de Investigacin Cientfica y Educacin Superior de Ensenada, (CICESE) [1]
References
1 Neutralizing Ability of a Single Domain VNAR Antibody: In Vitro Neutralization of SARS-CoV-2 Variants of Concern. Int J Mol Sci. 2022 Oct 14;23(20):12267.