General Information of Synthetic Binding Protein (SBP) (ID: SBP003420)
SBP Name
Bicyclic peptide anti-uPA UK504
Synonyms
Bicyclic peptide UK504
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
PDB ID 4GLY
Sequence Length 14
SBP Sequence
>Bicyclic peptide anti-uPA UK504
SCLGRGCENHRCL
3D Structure
Experimentally Validated Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS017
Scaffold Info
[1]
Scaffold Name Bicyclic peptide
Scaffold Class Non-Antibody
Fold Type Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Urokinase-type plasminogen activator
BTS Info
Inhibitor Research tool N.A. Swiss federal Institute of Technology in Lausanne [1]
References
1 Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries. J Am Chem Soc. 2013 May 1;135(17):6562-9.