Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003376) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv Emerfetamab
|
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| Synonyms |
Emerfetamab
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Phase I | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| T-cell surface glycoprotein CD3 epsilon chain | Binder | Acute myeloid leukaemia [ICD-11: XH8AA5] | N.A. | Amgen | [1] | |
| Myeloid cell surface antigen CD33 | Binder | Acute myeloid leukaemia [ICD-11: XH8AA5] | N.A. | Amgen | [1] | |