Details of the SBP

General Information of Synthetic Binding Protein (SBP) (ID: SBP003209)
SBP Name
DARPin anti-SARS-CoV-2 MP0423
Synonyms
DARPin MP0423
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS027
Scaffold Info
[1] , [2]
Scaffold Name DARPin
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Spike glycoprotein
BTS Info
Binder SARS-CoV-2 infection (COVID-19) [ICD-11: XN109] N.A. Molecular Partners; Novartis [1] , [2]
References
1 DARPins stack up as anti-COVID-19 agents. Nat Biotechnol. 2020 Dec;38(12):1369.
2 Molecular Partners. Product Development Pipeline. 2021.