Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP003029) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
DARPin anti-Fc-gamma-RIIA/RIIB clone D11_D11
|
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| Synonyms |
DARPin RIIB D11_D11
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS027 | [1] , [2] | ||||
| Scaffold Name | DARPin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Fc-gammaRIIB | Binder | Allergies [ICD-11: 4A84.Z] | Kd: 0.00063 nM | University of South Carolina | [1] , [2] | |
| Fc-gammaRIIA | Binder | Allergies [ICD-11: 4A84.Z] | Kd: 0.056 nM | University of South Carolina | [1] , [2] | |