General Information of Synthetic Binding Protein (SBP) (ID: SBP001807)
SBP Name
scFv anti-VEGF/SasA variants
Synonyms
Anti-VEGF/SasA scFv
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Template Name scFv Av1
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Vascular endothelial growth factor A
BTS Info
Binder Research tool N.A. Genomics Research Center [1]
Immunoglobulin G-binding protein A
BTS Info
Binder Research tool N.A. Genomics Research Center [1]
References
1 Antibody variable domain interface and framework sequence requirements for stability and function by high-throughput experiments. Structure. 2014 Jan 7;22(1):22-34.