General Information of Synthetic Binding Protein (SBP) (ID: SBP001491)
SBP Name
DARPin anti-IgE E2_79
Synonyms
DARPin E2_79
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS027
Scaffold Info
[1]
Scaffold Name DARPin
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Immunoglobulin E
BTS Info
Binder Allergies [ICD-11: 4A84.Z] N.A. ETH Zurich [1]
References
1 Sensing and responding to allergic response cytokines through a genetically encoded circuit. Nat Commun. 2017 Oct 24;8(1):1101.