General Information of Synthetic Binding Protein (SBP) (ID: SBP001445)
SBP Name
DARPin anti-NTSR1 P28
Synonyms
DARPin P28
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli XL1-Blue
Selection Method Ribosome display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS027
Scaffold Info
[1]
Scaffold Name DARPin
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Neurotensin receptor type 1
BTS Info
Binder Tools as an alternative binding molecule for co-crystallization Kd: 75 nM University of Zurich [1]
References
1 Selection and characterization of DARPins specific for the neurotensin receptor 1. Protein Eng Des Sel. 2009 Jun;22(6):357-66.