Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000983) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
VL dAb anti-B7.1 MB10
|
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| Synonyms |
VL dAb MB10
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>CDR1
RYSQSLFHRNWKTWVD >CDR2 AASIRAS >CDR3 MQGTHPY |
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| Template Name | VL B10503 | |||||
| Template Sequence |
>CDR1
RSSQSLLHSNGKTWLD >CDR2 AASIRAS >CDR3 MQGTYPY |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS064 | [1] | ||||
| Scaffold Name | VL dAb | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| T-lymphocyte activation antigen CD80 | Binder | Research tool | Kd: 191 nM | Dyax B.V. | [1] | |