Details of the SBP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000972)
SBP Name
Human VH dAb anti-Acr VH F1(M394E)
Synonyms
Human VH dAb F1(M394E)
Molecular Weight 18 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Discrete optimised potential energy score
Highest Status Research
Template Name Human VH domain antibody clone F1
Protein Scaffold Information of This SBP
Scaffold ID PS039
Scaffold Info
[1]
Scaffold Name Human VH dAb
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Alpha-crystallin
BTS Info
Binder Latent tuberculosis [ICD-11: 1B14] N.A. Universiti Sains Malaysia [1]
References
1 Optimisation of human V H domain antibodies specific to Mycobacterium tuberculosis heat shock protein (HSP16.3). J Comput Aided Mol Des. 2019 Mar;33(3):375-385.