Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000784) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Designed TPR protein anti-Dss1 T-Mods
|
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| Synonyms |
Designed TPR protein T-Mods
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Highest Status | Research | |||||
| Template Name | TPR2A domain | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS030 | [1] | ||||
| Scaffold Name | Designed TPR protein | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Beta-Turns | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| 26S proteasome complex subunit SEM1 | Inhibitor | Cancers [ICD-11: 2D4Z] | Kd: 175000 nM | Yale University | [1] | |