General Information of Synthetic Binding Protein (SBP) (ID: SBP000718)
SBP Name
VNAR anti-HEWL clone 754-2
Synonyms
vNAR clone 754-2
Molecular Weight 13.0 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BLT5403
Selection Method Phage display
Highest Status Research
Sequence Length 119
SBP Sequence
>VNAR anti-HEWL clone 754-2
MLGDPNSAHVDQTPRVATKETGESLTINCALRGAICGLYATSWFRQNPGSTGWERITIGG
RYVESVNKGSKSFSLQIKDLTVEDSVTFYCKATLLFILLCIALLSLLLAMMGLDRADCE
3D Structure
Computationally Modelled Structure
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Template Name vNAR HEL-5A7
Protein Scaffold Information of This SBP
Scaffold ID PS065
Scaffold Info
[1]
Scaffold Name vNAR
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Hen egg-white lysozyme
BTS Info
Binder Research tool N.A. Gyeongsang National University [1]
References
1 Construction of an artificially randomized IgNAR phage display library: screening of variable regions that bind to hen egg white lysozyme. Mar Biotechnol (NY). 2013 Feb;15(1):56-62.