Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP000704)
SBP Name	VNAR anti-EpCAM/Fc-gamma F1
Synonyms	VNAR F1
Molecular Weight	12 kDa
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method	Yeast display
Highest Status	Research
Template Name	vNAR 5005

Protein Scaffold Information of This SBP
Scaffold ID	PS065 Scaffold Info					[1]
Scaffold Name	vNAR
Scaffold Class	Antibody fragment
Fold Type	Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Fc gamma	BTS Info	Binder	Research tool	Kd: 2600 nM	Technical University of Darmstadt	[1]
Epithelial cell adhesion molecule	BTS Info	Binder	Research tool	Kd: 53 nM	Technical University of Darmstadt	[1]

References

1

The Shark Strikes Twice: Hypervariable Loop 2 of Shark IgNAR Antibody Variable Domains and Its Potential to Function as an Autonomous Paratope. Mar Biotechnol (NY). 2015 Aug;17(4):386-92.