Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000697) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
VNAR anti-EpCAM clone SH2
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| Synonyms |
VNAR SH2
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| Molecular Weight | 12.2 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Expi293F?human cells | |||||
| Selection Method | Yeast display | |||||
| Highest Status | Research | |||||
| Sequence Length | 110 | |||||
| SBP Sequence |
>VNAR anti-EpCAM clone SH2
MAARLEQTPTTTTKEAGESLTINCVLKPEWTILGRTYWYFTKKGATKKARLSTGGRYSDT KNTASKSFSLRISDLRVEDSGTYHCEALIYSDMGMIMWKIEGGGTPLTVK |
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| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Template Name | vNAR H3 and vNAR H5 | |||||
| Template Sequence |
>vNAR H3
MAARLEQTPTTTTKEAGESLTINCVLKGSGYVLGRTYWYFTKKGATKKASLSTGGRYSDT KNTASKSFSLRISDLRVEDSGTYHCEALIYSDMGMIMWKIEGGGTVLTVN >vNAR H5 MAPRLEQTPTTTTKEAGESLTINCVLKGSSCTLGSTYWCFTKKGATKKASLSTGGRYSDT KNTASKSFSLRISDLRVEDSGTYHCEATIWDMDKGQRHRIEGGGTILTVK |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS065 | [1] | ||||
| Scaffold Name | vNAR | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
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| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Epithelial cell adhesion molecule | Binder | Research tool | N.A. | Technical University of Darmstadt | [1] | |