Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000695) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
VNAR anti-EpCAM H5
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| Synonyms |
VNAR H5
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| Molecular Weight | 12.0 kDa | |||||
| Thermal Denaturation TEMP | 71.5 ℃ | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli MBH 71-18 | |||||
| Selection Method | Yeast display | |||||
| Highest Status | Research | |||||
| Sequence Length | 110 | |||||
| SBP Sequence |
>VNAR anti-EpCAM H5
MAPRLEQTPTTTTKEAGESLTINCVLKGSSCTLGSTYWCFTKKGATKKASLSTGGRYSDT KNTASKSFSLRISDLRVEDSGTYHCEATIWDMDKGQRHRIEGGGTILTVK |
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| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS065 | [1] , [2] | ||||
| Scaffold Name | vNAR | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
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| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Epithelial cell adhesion molecule | Binder | Research tool | Kd: 1030 nM | Technical University of Darmstadt | [1] , [2] | |
| References |
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