General Information of Synthetic Binding Protein (SBP) (ID: SBP000687)
SBP Name
VNAR anti-HEWL Ly-X20
Synonyms
VNAR Ly-X20
Molecular Weight 12.0 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Sequence Length 113
SBP Sequence
>VNAR anti-HEWL Ly-X20
ARVDQTPRSVTKETGESLTINCVLRDASYALGSTCWYRKKSGEGNEESISKGGRYVETVN
SGSKSFSLRINDLTVEDGGTYRCGLGVAGGYCDYALCSSRYADCGDGTAVTVN
3D Structure
Computationally Modelled Structure
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Template Name vNAR HEL-5A7
Protein Scaffold Information of This SBP
Scaffold ID PS065
Scaffold Info
[1]
Scaffold Name vNAR
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Hen egg-white lysozyme
BTS Info
Binder Research tool N.A. University of Aberdeen [1]
References
1 Rapid isolation of IgNAR variable single-domain antibody fragments from a shark synthetic library. Mol Immunol. 2007 Jan;44(4):656-65.