General Information of Synthetic Binding Protein (SBP) (ID: SBP000682)
SBP Name
VNAR anti-NP DSTL097
Synonyms
VNAR DSTL097
Molecular Weight 14.2 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Bacteria
Selection Method Phage display
Highest Status Research
Sequence Length 133
SBP Sequence
>VNAR anti-NP DSTL097
MKYLLPTAAAGLLLLAAQPAMARVDQTPRSVTKETGESLTINCVLRDATYALGSTCWYRK
KSGSTNEESIWKGGRYVETVNSGSKSFSLRINDLTVEDGGTYRCGVSEVNWCGVAGLRCP
VDACGDGTAVTVN
3D Structure
Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS065
Scaffold Info
[1]
Scaffold Name vNAR
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Nucleoprotein
BTS Info
Binder Tools for detecting Ebolavirus infection N.A. Defence Science and Technology Laboratory [1]
References
1 Isolation and characterisation of Ebolavirus-specific recombinant antibody fragments from murine and shark immune libraries. Mol Immunol. 2011 Sep;48(15-16):2027-37.