Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000665) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
alphaRep protein anti-Alpha-tubulin iE5
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| Synonyms |
alphaRep protein iE5
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| Molecular Weight | 23.6 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli BL21 (DE3) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| PDB ID | 6GWC | |||||
| Sequence Length | 219 | |||||
| SBP Sequence |
>alphaRep protein anti-Alpha-tubulin iE5
EKVEMYIKNLQDDSTLVRSIAAAALGKIGDERAVEPLIKALKDEDSRVRAQAAGALGQIG DERAVEPLIKALKDEDPSVRYRAAEALGKIGDERAVEPLIKALKDEDTTVRRIAATALGK IGDERAVEPLIKALKDEDAAVRLTAARALGEIGDERAVEPLIKALKDEDAYVRRAAAQAL GKIGGERVRAAMEKLAETGTGFARKVAVNYLETHKSLIS |
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| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS009 | [1] | ||||
| Scaffold Name | Alpha-Rep protein | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Alpha-Helices + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
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| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Tubulin alpha-1A chain | Binder | Research tool | Kd: 270 nM | Institute for Integrative Biology of the Cell (I2BC) | [1] | |