Details of the BTS
General Information of Binding Target of SBP (BTS) (ID: ST00056) | ||||||
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BTS Name |
Tubulin alpha-1A chain
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Synonyms |
Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain
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BTS Type |
Protein
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Family |
Tubulin family
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Gene Name |
TUBA1A
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Organism |
Homo sapiens (Human)
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Function |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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UniProt ID | ||||||
UniProt Entry | ||||||
PFam | ||||||
Gene ID | ||||||
Sequence |
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE AREDMAALEKDYEEVGVDSVEGEGEEEGEEY |
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Sequence Length |
451
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Synthetic Binding Protein (SBP) Targeting This BTS |
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SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
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alphaRep protein anti-Alpha-tubulin iE5 | Research | Binder | Kd: 270 nM | Research tool | [1] | |
alphaRep protein anti-Alpha-tubulin iiH5 | Research | Binder | Kd: 95 nM | Research tool | [1] | |
alphaRep protein anti-Alpha-tubulin iiiA5 | Research | Binder | Kd: 5 nM | Tools for understanding nucleation | [2] | |