Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000646) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Affitin anti-HEWL H4
|
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| Synonyms |
Affitin H4
|
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| Molecular Weight | 7.6 kDa | |||||
| Thermal Denaturation TEMP | 67.4 ℃ | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Ribosome display | |||||
| Highest Status | Research | |||||
| PDB ID | 4CJ2 | |||||
| Sequence Length | 65 | |||||
| SBP Sequence |
>Affitin anti-HEWL H4
MVKVKFFWNGEEKEVDTSKIVWVKRAGKSVLFIYDDNGYGDVTEKDAPKELLDMLARAER EKKLN |
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| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Template Name | Sac7d | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS007 | [1] | ||||
| Scaffold Name | Affitin | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | One Alpha-Helix + Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Hen egg-white lysozyme | Inhibitor | Tools for inhibiting of glycosidases | Kd: 11 nM | Institut Pasteur de Montevideo; Institut Pasteur | [1] | |