General Information of Synthetic Binding Protein (SBP) (ID: SBP000600)
SBP Name
Evibody anti-HEWL clys12
Synonyms
Evibody clys12
Molecular Weight 15 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Ribosome display
Highest Status Research
SBP Sequence
>CDR1
SPGQRHKWV
>CDR2
TYMMGNELTFL
>CDR3
EPIFLSPSSASAHCL
Template Name CTLA-4
Template Sequence
>CDR1
SPGKATEVRV
>CDR2
TYMMGNELTFL
>CDR3
ELMYPPPYYL
Protein Scaffold Information of This SBP
Scaffold ID PS033
Scaffold Info
[1]
Scaffold Name Evibody
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Hen egg-white lysozyme
BTS Info
Binder Cancers [ICD-11: 2D4Z] N.A. CSIRO Health Sciences and Nutrition and CRC for Diagnostic Technologies [1]
References
1 Ribosome display and affinity maturation: from antibodies to single V-domains and steps towards cancer therapeutics. J Immunol Methods. 2001 Feb 1;248(1-2):31-45.