Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000576) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Beta-Hairpin mimetic anti-CXCR4 POL2438
|
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| Synonyms |
Beta-Hairpin mimetic POL2438
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>Beta-Hairpin mimetic anti-CXCR4 POL2438
PYR[Citrulline]CRG[d-Pro]RR[2-Naphthylalanine]CY[Citrulline] K[d-Pro] |
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| Sequence Description | The first Pro and the last dPro are linked by a chemical bond. | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS016 | [1] | ||||
| Scaffold Name | Beta-Hairpin mimetic | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Beta-Turn | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| C-X-C chemokine receptor type 4 | Inhibitor | Human immunodeficiency virus infection (HIV infection) [ICD-11: 1C62.Z] | N.A. | University of Zurich | [1] | |