Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000559) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Cyclotide anti-VEGF-A
|
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| Synonyms |
Cpr-cyclotide
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS023 | [1] | ||||
| Scaffold Name | Cyclotide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Vascular endothelial growth factor A | Inhibitor | Cancers [ICD-11: 2D4Z]; Rheumatoid arthritis [ICD-11: FA20.Z] | N.A. | University of Queensland | [1] | |