Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000503) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Affibody anti-ERBB3 Z(08698)
|
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| Synonyms |
Affibody Z(08698)
|
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| Molecular Weight | 6.5 kDa | |||||
| Thermal Denaturation TEMP | 64 ℃ | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli Rosetta (DE3) | |||||
| Selection Method | Staphylococcal surface display and Fluorescence-activated cell sorting | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS004 | [1] | ||||
| Scaffold Name | Affibody | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Three Alpha-Helices | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Receptor tyrosine-protein kinase erbB-3 | Inhibitor | Tumors [ICD-11: XH1N44] | Kd: 0.05 nM | Royal Institute of Technology | [1] | |