General Information of Synthetic Binding Protein (SBP) (ID: SBP000476)
SBP Name
Affibody anti-IgE clone Z
Synonyms
Affibody Z(IgE)
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Staphylococcus carnosus
Selection Method Staphylococcal surface display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS004
Scaffold Info
[1]
Scaffold Name Affibody
Scaffold Class Non-Antibody
Fold Type Three Alpha-Helices
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Immunoglobulin E
BTS Info
Binder Research tool Kd: 400 nM Royal Institute of Technology (KTH) [1]
References
1 Staphylococcal surface display of immunoglobulin A (IgA)- and IgE-specific in vitro-selected binding proteins (affibodies) based on Staphylococcus aureus protein A. Appl Environ Microbiol. 1999 Sep;65(9):4134-40.