General Information of Synthetic Binding Protein (SBP) (ID: SBP000450)
SBP Name
Affibody anti-Apo-A-1 clone 24:4
Synonyms
Alpha-Apolipo 24: 4
Molecular Weight 6.3 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Sequence Length 58
SBP Sequence
>Affibody anti-Apo-A-1 clone 24:4
VDNKFNKDKNNAAVEIMQLPNLNAGQILAFIISLPDDPSQSANLLAEAKKLNDAQAPK
3D Structure
Computationally Modelled Structure
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Template Name Z domain of staphylococcal protein A
Protein Scaffold Information of This SBP
Scaffold ID PS004
Scaffold Info
[1]
Scaffold Name Affibody
Scaffold Class Non-Antibody
Fold Type Three Alpha-Helices
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Apolipoprotein A-I
BTS Info
Binder Tools for specific binding to different target proteins Kd: 1000 nM Royal Institute of Technology [1]
References
1 Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain. Nat Biotechnol. 1997 Aug;15(8):772-7.